Anesthesiologist–Intensivist | Innovation Lead, Cleveland Clinic | AI in Healthcare & Critical Care | BrainX Co-founder | Patient Safety & Quality | MD, FCCM, FASA, FAMIA

Piyush Mathur, MD, FCCM, FASA, FAMIA is an anesthesiologist–intensivist and academic leader operating at the intersection of clinical medicine, artificial intelligence, and healthcare systems innovation. With over two decades of experience, his work focuses on advancing data-driven, human-centered approaches to care delivery.

At the Cleveland Clinic, he serves as Innovation Lead for the Department of Anesthesiology and has held multiple leadership roles across quality improvement, compliance, and medical education. His work has consistently centered on improving patient safety, perioperative quality, and large-scale clinical transformation.

Dr. Mathur is internationally recognized for his contributions to artificial intelligence in healthcare, with a particular focus on generative AI and large language models. His research and publications advance rigorous methods for evaluating and implementing AI in real-world clinical settings.

Within the CaPER Global Insight Circle, he brings a critical lens on how emerging technologies can be responsibly integrated into healthcare systems, balancing innovation with safety, validation, and human oversight.

His work reflects a commitment to bridging medicine, data science, and systems thinking to shape the future of healthcare.